DNA芯片分析儀(dChip)(www.dchip.org)是一種用于探測級別(例如Affymetrix公司的平臺)和高層次的基因表達微陣列和SNP微陣列(李和黃2001年,林等人 2004年分析的Windows軟件)。
或從不同的基因表達微陣列平臺SNP數(shù)據(jù)分析,也可以作為外部數(shù)據(jù)集進口。在探頭水平,dChip可以顯示和正;募⒒谀P偷姆椒ㄊ箙R集跨多個陣列和自動探頭的選擇來處理交叉雜交和圖像信息的污染。高級別dChip分析包括比較樣本,層次聚類,觀點表達以及染色體,陸和SNP單核苷酸多態(tài)性數(shù)據(jù),并復(fù)制陣列數(shù)量分析,連鎖分析。在這些功能基因的信息資料和樣品的分析結(jié)果與相關(guān)性。
DNA芯片分析軟件,似乎是兩個華人開發(fā)的軟件。
英文介紹:
DNA-Chip Analyzer (dChip) (www.dchip.org) is a Windows software package for probe-level (e.g. Affymetrix platform) and high-level analysis of gene expression microarrays and SNP microarrays (Li and Wong 2001a, Lin et al. 2004). Gene expression or SNP data from various microarray platforms can also be analyzed by importing as external dataset. At the probe level, dChip can display and normalize the CEL files, and the model-based approach allows pooling information across multiple arrays and automatic probe selection to handle cross-hybridization and image contamination. High-level analysis in dChip includes comparing samples, hierarchical clustering, view expression and SNP data along chromosome, LOH and copy number analysis of SNP arrays, and linkage analysis. In these functions the gene information and sample information are correlated with the analysis results.